Evinacumab, CAS 1446419-85-7

Product Description: Evinacumab (REGN1500) is a human anti-ANGPTL3 (angiopoietin-like protein 3) monoclonal antibody (IgG4 class antibody). Evinacumab reduces plasma lipids in dyslipidemic mice by blocking ANGPTL3. Evinacumab can be used in studies of homozygous familial hypercholesterolaemia (HoFH), refractory hypercholesterolaemia (both familial and non-familial) and severe hypertriglyceridaemia[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: N/A

References: [1]Gusarova V, et al. ANGPTL3 blockade with a human monoclonal antibody reduces plasma lipids in dyslipidemic mice and monkeys. J Lipid Res. 2015 Jul;56(7):1308-17.

CAS Number: 1446419-85-7

Molecular Weight: N/A

Compound Purity: 98.98

Research Area: Metabolic Disease; Cardiovascular Disease

Solubility: 10 mM in DMSO

Target: Others

• SKU: MEXHY-P99194-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99194-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK