Ianalumab, CAS 1929549-92-7

Product Description: Ianalumab (VAY-736) is a human, decarboxylated antibody against BAFF-R. Ianalumab can block the interaction between BAFF and BAFF-R and antagonize the apoptosis protection mediated by BAFF. Ianalumab exerts antibody-dependent cytotoxic (ADCC), depending on effector cell activation mediated by immune receptor tyrosine activation motif (ITAM)[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]McWilliams EM, et al. Anti-BAFF-R antibody VAY-736 demonstrates promising preclinical activity in CLL and enhances effectiveness of ibrutinib. Blood Adv. 2019 Feb 12;3(3):447-460.

CAS Number: 1929549-92-7

Molecular Weight: N/A

Compound Purity: 95.00

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Others

• SKU: MEXHY-P99653-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99653-10
• Package Unit: 10 mg
• Quantity Unit: STK
• Conjugate: Unconjugated