Lacnotuzumab, CAS 1831128-32-5

Product Description: Lacnotuzumab (MCS110) is a neutralizing humanized IgG1/κ monoclonal antibody targeting CSF-1 that prevents CSF-1 from activating the CSF-1R. Lacnotuzumab can be used for the research of pigmented villonodular synovitis[1][2].

Formula: N/A

References: [1]Kuemmel S, et, al. A Randomized Phase II Study of Anti-CSF1 Monoclonal Antibody Lacnotuzumab (MCS110) Combined with Gemcitabine and Carboplatin in Advanced Triple-Negative Breast Cancer. Clin Cancer Res. 2022 Jan 1;28(1):106-115./[2]Pognan F, et, al. Colony-Stimulating Factor-1 Antibody Lacnotuzumab in a Phase 1 Healthy Volunteer Study and Mechanistic Investigation of Safety Outcomes. J Pharmacol Exp Ther. 2019 Jun;369(3):428-442.

CAS Number: 1831128-32-5

Molecular Weight: N/A

Research Area: Cancer; Metabolic Disease

Solubility: H2O

Target: c-Fms

• SKU: MEXHY-P99368-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99368-5
• Green Labware: No
• Package Unit: 5mg
• Quantity Unit: STK