Letaplimab, CAS 2283356-07-8

Product Description: Letaplimab (IBI-188) is a human IgG4 anti-CD47 monoclonal antibody. CD47 is overexpressed on cancer cells, it is a ligand for SIRPα. Letaplimab enhances tumor cell phagocytosis[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Miao Miao, et al. A Phase 1b Study to Evaluate Safety and Efficacy of IBI188 in Combination with Azacitidine (AZA) As a First-Line Treatment in Subjects with Newly Diagnosed Higher Risk Myelodysplastic Syndrome. MYELODYSPLASTIC SYNDROMES-CLINICAL AND EPIDEMIOLOGICAL NOVEMBER 15, 2022.

CAS Number: 2283356-07-8

Molecular Weight: N/A

Compound Purity: 95.00

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Others

• SKU: MEXHY-P99700-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99700-1
• Package Unit: 1 mg
• Quantity Unit: STK
• Conjugate: Unconjugated