Lirentelimab, CAS 2283348-97-8

Product Description: Lirentelimab (AK002) is a humanized IgG1 monoclonal antibody that targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). Lirentelimab induces cell apoptosis of IL-5-activated eosinophils and inhibits IgE-mediated mast cell activation. Lirentelimab can be used for the research of eosinophilic gastritis and duodenitis[1].

Applications: COVID-19-immunoregulation

Formula: N/A

References: [1]Youngblood BA, et al. AK002, a Humanized Sialic Acid-Binding Immunoglobulin-Like Lectin-8 Antibody that Induces Antibody-Dependent Cell-Mediated Cytotoxicity against Human Eosinophils and Inhibits Mast Cell-Mediated Anaphylaxis in Mice. Int Arch Allergy Immunol. 2019;180(2):91-102.

CAS Number: 2283348-97-8

Molecular Weight: N/A

Compound Purity: 99.91

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Apoptosis

• SKU: MEXHY-P99371-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99371-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK