Losatuxizumab, CAS 1801544-27-3

Product Description: Losatuxizumab (ABT-806) is an anti-EGFR monoclonal antibody. Losatuxizumab binds to EGFR with EC50s of 0.96 nM for EGFR wild-type, 0.09 nM for EGFRC271A,C283A, 0.12 nM for EGFRvIII, 0.66 nM for EGFR1-501. Losatuxizumab can be used for research of EGFR-expressing cancers[1][2].

Applications: Cancer-Kinase/protease

Formula: N/A

References: [1]Reilly EB, et al. Characterization of ABT-806, a Humanized Tumor-Specific Anti-EGFR Monoclonal Antibody. Mol Cancer Ther. 2015 May;14(5):1141-51. /[2]Phillips AC, et al. ABT-414, an Antibody-Drug Conjugate Targeting a Tumor-Selective EGFR Epitope. Mol Cancer Ther. 2016 Apr;15(4):661-9.

CAS Number: 1801544-27-3

Molecular Weight: N/A

Compound Purity: 95.00

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: EGFR

• SKU: MEXHY-P99715-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99715-5
• Package Unit: 5 mg
• Quantity Unit: STK
• Conjugate: Unconjugated