Luspatercept, CAS 1373715-00-4

Product Description: Luspatercept (ACE-536) is a recombinant modified ActRIIB fusion protein that binds with transforming growth factor β superfamily ligands. Luspatercept increases the erythrocyte numbers and promotes maturation of erythroid precursors. Luspatercept binds with GDF11 and inhibits Smad2/3 signaling. Luspatercept can be used for the research of anemia[1].

Applications: Metabolism-protein/nucleotide metabolism

Formula: N/A

References: [1]Suragani RN, et al. Transforming growth factor-β superfamily ligand trap ACE-536 corrects anemia by promoting late-stage erythropoiesis. Nat Med. 2014 Apr;20(4):408-14.

CAS Number: 1373715-00-4

Molecular Weight: N/A

Compound Purity: 98.92

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: TGF-beta/Smad

• SKU: MEXHY-P99720-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99720-1
• Package Unit: 1 mg
• Quantity Unit: STK
• Conjugate: Unconjugated