Mavrilimumab, CAS 1085337-57-0

Product Description: Mavrilimumab (CAM 3001) is a monoclonal antibody that binds to the α subunit of the granulocyte-macrophage colony stimulating factor (GM-CSF) receptor and blocks intracellular signalling downstream of GM-CSF. GM-CSF might be a mediator of the hyperactive inflammatory response associated with respiratory failure and death[1].

Applications: COVID-19-immunoregulation

Formula: N/A

References: [1]Paul C Cremer, et al. Mavrilimumab in patients with severe COVID-19 pneumonia and systemic hyperinflammation (MASH-COVID): an investigator initiated, multicentre, double-blind, randomised, placebo-controlled trial. Lancet Rheumatol. 2021 Jun;3(6):e410-e41

CAS Number: 1085337-57-0

Molecular Weight: N/A

Compound Purity: 98.37

Research Area: Inflammation/Immunology; Cardiovascular Disease

Solubility: H2O

Target: c-Fms

• SKU: MEXHY-P99031-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99031-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK