Natalizumab (Solution), CAS 189261-10-7

Product Description: Natalizumab (Solution) is a recombinant, humanized IgG4 monoclonal antibody, binds to α4β1-integrin and blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1). Natalizumab can be used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease. Natalizumab is also the first targeted therapy which blocks an essential mechanism for lymphocyte entry to the CNS and thus prevents acute demyelinating relapses[1].

Applications: COVID-19-immunoregulation

Formula: N/A

References: [1]Hutchinson M. Natalizumab: A new treatment for relapsing remitting multiple sclerosis. Ther Clin Risk Manag. 2007 Jun;3(2):259-68.

CAS Number: 189261-10-7

Molecular Weight: N/A

Compound Purity: 98.72

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Integrin

• SKU: MEXHY-108831A-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-108831A-25
• Green Labware: No
• Package Unit: 25 mg
• Quantity Unit: STK