Pembrolizumab (anti-PD-1)

Product Description: Pembrolizumab (anti-PD-1) is a humanized IgG4 antibody and PD-1 inhibitor. Pembrolizumab produces PD-1 blockade, preventing PD-L1 and PD-L2 from connecting to PD-1. This avoids the uncontrolled regulation of T cells on cells that normally express PD-1[1][2].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Schachter J, et al. Pembrolizumab versus ipilimumab for advanced melanoma: final overall survival results of a multicentre, randomised, open-label phase 3 study (KEYNOTE-006). Lancet. 2017 Aug 16. pii: S0140-6736(17)31601-X./[2]England CG, et al. Preclinical Pharmacokinetics and Biodistribution Studies of 89Zr-Labeled Pembrolizumab. J Nucl Med. 2017 Jan;58(1):162-168.

Molecular Weight: N/A

Compound Purity: 99.90

Research Area: Cancer

Solubility: H2O

Target: PD-1/PD-L1

• SKU: MEXHY-P9902A-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P9902A-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK