Product Description: Pepinemab (VX 15/2503) is a human monoclonal antibody against SEMA4D, a signalling protein 4D (SEMA4D), also known as CD100, which is a regulator of neuronal development and plays a role in a variety of cellular processes. Pepinemab can be used in the study of various neurodegenerative diseases such as Alzheimer's disease by blocking the activity of SEMA4D[1].
Formula: N/A
References: [1]Elizabeth E Evans, et al. Semaphorin 4D is upregulated in neurons of diseased brains and triggers astrocyte reactivity. J Neuroinflammation. 2022 Aug 6;19(1):200.
CAS Number: 2097151-87-4
Molecular Weight: N/A
Compound Purity: 97.55
Research Area: Neurological Disease
Solubility: 10 mM in DMSO
Target: Others