Ponsegromab, CAS 2368950-15-4

Product Description: Ponsegromab (PF 06946860) is a potent and selective humanized anti-GDF15 antibody inhibitor with anti-cachexia activity. Ponsegromab binds to GDF15 and prevents the binding of GDF15 to GFRAL, thereby blocking GDF15/GFRAL-mediated signaling. Ponsegromab can be used in the research of cancers[1].

Applications: Cancer-Kinase/protease

Formula: N/A

References: [1]E.J. Roeland, et al. 1696TiP Phase Ib study to assess the effect of PF-06946860 on appetite following subcutaneous administration in patients with anorexia and advanced cancer. VOLUME 32, SUPPLEMENT 5, S1185, SEPTEMBER 01, 2021. Annals of oncology.

CAS Number: 2368950-15-4

Molecular Weight: N/A

Compound Purity: 96.11

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: TGF-beta/Smad

• SKU: MEXHY-P99241-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99241-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK