Product Description: Raleukin (AMG-719) is a recombinant, nonglycosylated human interleukin-1 receptor (IL-1R) antagonist. Raleukin (AMG-719) is the first biological agent to block the pro-inflammatory effects[1][2].
Applications: Cancer-programmed cell death
Formula: C759H1186N208O232S10
References: [1]Cvetkovic RS, et al. Anakinra. BioDrugs. 2002;16(4):303-11; discussion 313-4./[2]McCall M, et al. Anakinra potentiates the protective effects of etanercept in transplantation of marginal mass human islets in immunodeficient mice. Am J Transplant. 2012 Feb;12(2):322-9./[3]Harnack U, et al. IL-1 receptor antagonist anakinra enhances tumour growth inhibition in mice receiving peptide vaccination and beta-(1-3),(1-6)-D-glucan. Anticancer Res. 2010 Oct;30(10):3959-65.
CAS Number: 143090-92-0
Molecular Weight: 17257.60
Compound Purity: 99.40
Research Area: Cancer; Inflammation/Immunology
Solubility: H2O
Target: Interleukin Related
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