Riliprubart, CAS 2756228-76-7

Product Description: Riliprubart (SAR445088) is an anti-C1s humanized monoclonal antibody that inhibits activated C1s in the proximal portion of the classical complement system. Riliprubart selectively inhibits activated C1s and prevents the enzymatic action of C1 on its substrates C4 and C2, thus inhibiting the formation of the classical pathway C3 convertase, C4b2a[1].

Applications: COVID-19-immunoregulation

Formula: N/A

References: [1]Timothy Chow, et al. First-in-human study with SAR445088: A novel selective classical complement pathway inhibitor. Clin Transl Sci. 2023 Apr;16(4):673-685.

CAS Number: 2756228-76-7

Molecular Weight: N/A

Compound Purity: 99.90

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Complement System

• SKU: MEXHY-P990091-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P990091-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK