Sabatolimab, CAS 2252262-24-9

Product Description: Sabatolimab (MBG453) is a high-affinity, humanized, IgG4 (S228P) antibody targeting TIM-3, an inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab is a potential immunosuppression agent that can target TIM-3 on immune and myeloid cells[1].

Applications: COVID-19-immunoregulation

Formula: N/A

References: [1]Andrew M. Brunner, et al. Efficacy and Safety of Sabatolimab (MBG453) in Combination with Hypomethylating Agents (HMAs) in Patients with Acute Myeloid Leukemia (AML) and High-Risk Myelodysplastic Syndrome (HR-MDS): Updated Results from a Phase 1b Study. Blood (2020) 136 (Supplement 1): 1–2.

CAS Number: 2252262-24-9

Molecular Weight: N/A

Compound Purity: 99.14

Research Area: Inflammation/Immunology

Solubility: H2O

Target: Tim3

• SKU: MEXHY-P99044-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99044-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK