Surzebiclimab

Product Description: Surzebiclimab (BGB-A425) is a humanized IgG1-variant monoclonal antibody against T-cell immunoglobulin and mucin-domain containing-3 (TIM-3). Surzebiclimab binds to the extracellular domain of human Tim-3 with high affinity (KD=0.36 nM) and specificity. Surzebiclimab can be used in research of cancer[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Tong Z, et, al. Abstract 2628: BGB-A425: a humanized anti-human Tim-3 antibody that exhibits strong immune cell activation. Cancer Res. 2017;77:(13_Supplement):2628.

Molecular Weight: N/A

Compound Purity: 95.00

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Mucin

• SKU: MEXHY-P99962-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99962-5
• Package Unit: 5 mg
• Quantity Unit: STK
• Conjugate: Unconjugated