Talquetamab, CAS 2226212-40-2

Product Description: Talquetamab (JNJ-64407564) is a humanized bispecific antibody that binds to GPRC5D (member of G protein-coupled receptor family C5 group D) and CD3 to induce T cell-mediated killing of GPRC5D-expressing MM cells through T cell recruitment and activation. Talquetamab (JNJ-64407564) has antitumor activity[1][2].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Christie P M Verkleij, et al. Preclinical activity and determinants of response of the GPRC5DxCD3 bispecific antibody talquetamab in multiple myeloma. Blood Adv. 2021 Apr 27;5(8):2196-2215./[2]Kodandaram Pillarisetti, et al. A T-cell-redirecting bispecific G-protein-coupled receptor class 5 member D x CD3 antibody to treat multiple myeloma. Blood. 2020 Apr 9;135(15):1232-1243.

CAS Number: 2226212-40-2

Molecular Weight: 146000

Compound Purity: 98.52

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: CD3

• SKU: MEXHY-P99394-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99394-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK