Teneliximab, CAS 299423-37-3

Product Description: Teneliximab (BMS-224819) is a chimeric monoclonal antibody, blocks the CD40-CD40L interaction. Teneliximab (BMS-224819) has partial agonist activity resulting in some signaling through CD40 and peripheral B cell depletion[1].

Applications: COVID-19-anti-virus

Formula: N/A

References: [1]Maria A Argiriadi, et al. CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches. BMC Mol Cell Biol. 2019 Aug 5;20(1):29./[2]Andrew B Adams, et al. Development of a chimeric anti-CD40 monoclonal antibody that synergizes with LEA29Y to prolong islet allograft survival. J Immunol. 2005 Jan 1;174(1):542-50.

CAS Number: 299423-37-3

Molecular Weight: N/A

Compound Purity: 99.0

Research Area: Cancer; Inflammation/Immunology

Solubility: 10 mM in H2O

Target: TNF Receptor

• SKU: MEXHY-P99321-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99321-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK