Tepoditamab, CAS 2044679-53-8

Product Description: Tepoditamab (MCLA-117) is a bispecific monoclonal antibody that binds to CLEC12A of myeloid cells and CD3 of cytotoxic T cells. Among others, CLEC12A is a myeloid differentiation antigen. Tepoditamab (MCLA-117) kills AML leukaemia mother cells and AML leukaemia stem cells, induces T cell-mediated proliferative lysis of AML cells and can be used in acute myeloid leukaemia (AML) research[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Naval Daver, et al. T-cell-based immunotherapy of acute myeloid leukemia: current concepts and future developments. Leukemia. 2021 Jul;35(7):1843-1863.

CAS Number: 2044679-53-8

Molecular Weight: N/A

Compound Purity: 92.63

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: CD3

• SKU: MEXHY-P99390-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99390-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK