Tregalizumab, CAS 1207446-68-1

Product Description: Tregalizumab is a humanized anti-human CD4 monoclonal antibody (IgG1 type) that selectively activates the suppressive properties of regulatory T cells (Tregs) in vitro. Tregalizumab can be used in the research of autoimmune diseases (resulting from insufficient Treg activity) and allergies[1][2][3].

Applications: COVID-19-immunoregulation

Formula: N/A

References: [1]König M, et al. Tregalizumab - A Monoclonal Antibody to Target Regulatory T Cells. Front Immunol. 2016 Jan 25;7:11. /[2]Vogel S, et al. Antibody induced CD4 down-modulation of T cells is site-specifically mediated by CD64(+) cells. Sci Rep. 2015 Dec 16;5:18308. /[3]Helling B, et al. A specific CD4 epitope bound by tregalizumab mediates activation of regulatory T cells by a unique signaling pathway. Immunol Cell Biol. 2015 Apr;93(4):396-405.

CAS Number: 1207446-68-1

Molecular Weight: N/A

Compound Purity: 98.97

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Others

• SKU: MEXHY-P99327-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99327-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK