TSR-033, CAS 2225940-96-3

Product Description: TSR-033 is a high affinity human IgG4 antibody targeting LAG-3 (lymphocyte activation gene-3), a co-receptor associated with impaired T cell function and often co-expressed with PD-1, that enhances T cell function and PD-1 blocking activity in vitro and in vivo. TSR-033 has anti-tumor activity[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Srimoyee Ghosh, et al. TSR-033, a Novel Therapeutic Antibody Targeting LAG-3, Enhances T-Cell Function and the Activity of PD-1 Blockade In Vitro and In Vivo. Mol Cancer Ther. 2019 Mar;18(3):632-641.

CAS Number: 2225940-96-3

Molecular Weight: N/A

Compound Purity: 95.25

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: LAG-3

• SKU: MEXHY-P99387-10
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99387-10
• Green Labware: No
• Package Unit: 10 mg
• Quantity Unit: STK