Product Description: Valanafusp alfa (AGT-181) is a brain penetrating recombinant fusion protein of a chimeric monoclonal antibody against the human insulin receptor (HIR) and human iduronidase (IDUA). Valanafusp alfa can be used for the research of Mucopolysaccharidosis type I (MPS I) [1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: N/A
References: [1]Boado RJ, et al. AGT-181: expression in CHO cells and pharmacokinetics, safety, and plasma iduronidase enzyme activity in Rhesus monkeys. J Biotechnol. 2009 Oct 26;144(2):135-41./[2]Boado RJ, et al. Genetic engineering of a lysosomal enzyme fusion protein for targeted delivery across the human blood-brain barrier. Biotechnol Bioeng. 2008 Feb 1;99(2):475-84.
CAS Number: 1815583-32-4
Molecular Weight: N/A
Compound Purity: 98.42
Research Area: Metabolic Disease
Solubility: H2O
Target: Insulin Receptor
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