Product Description: Volagidemab is an antagonistic glucagon receptor (GCGR) monoclonal antibody (mAb). Volagidemab can be used in the research of type 1 diabetes (T1D)[1][2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: N/A
References: [1]Pettus J, et al. Glucagon receptor antagonist volagidemab in type 1 diabetes: a 12-week, randomized, double-blind, phase 2 trial. Nat Med. 2022 Oct;28(10):2092-2099. /[2]Wang MY, et al. Glucagon receptor antibody completely suppresses type 1 diabetes phenotype without insulin by disrupting a novel diabetogenic pathway. Proc Natl Acad Sci U S A. 2015 Feb 24;112(8):2503-8.
CAS Number: 1233956-13-2
Molecular Weight: N/A
Compound Purity: 98.43
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: GCGR