XmAb 5592, CAS 1221901-33-2

Product Description: XmAb 5592 is a humanized, Fc-engineered anti-HM1.24 antibody with enhanced binding to FcγRIIIa and FcγRIIa receptors, augments HM1.24-specific multiple myeloma (MM) cells lysis in vitro via antibody-dependent cellular cytotoxicity (ADCC) and antibody dependent cellular phagocytosis (ADCP)[1].

Applications: Cancer-programmed cell death

Formula: N/A

References: [1]Tai YT, et, al. Potent in vitro and in vivo activity of an Fc-engineered humanized anti-HM1.24 antibody against multiple myeloma via augmented effector function. Blood. 2012 Mar 1;119(9):2074-82.

CAS Number: 1221901-33-2

Molecular Weight: N/A

Compound Purity: 99.51

Research Area: Cancer

Solubility: 10 mM in DMSO

Target: Others

• SKU: MEXHY-P99381-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P99381-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK