ATG4B Blocking peptide (C terminal region)

Description of Target: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Product Format: Lyophilized powder

Protein Size: 331

• SKU: AVIAAP97039-100
• Manufacturer: Aviva Systems Biology
• Manufacturer SKU: AAP97039-100UG
• Green Labware: No
• Package Unit: 100µg
• Quantity Unit: STK
• Application: Western Blotting
• Human Gene ID: 23192