CCM2 Blocking Peptide (N terminal)

Description of Target: This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.

Product Format: Lyophilized powder

Protein Size: 465

• SKU: AVIAAP60630-100
• Manufacturer: Aviva Systems Biology
• Manufacturer SKU: AAP60630-100UG
• Green Labware: No
• Package Unit: 100µg
• Quantity Unit: STK
• Application: Western Blotting
• Human Gene ID: 83605