Presentation: Sterile solution in PBS, pH 7.4, 10% Glycerol.
Description: Nsp10 have shown that it is a 15-kDa protein of unknown function that has been shown to interact with itself, nsp1, and nsp7. It colocalizes with N to sites of viral replication and is essential for replication. It plays a pivotal role in viral transcription by stimulating both nsp14 3'-5' exoribonuclease and nsp16 2'-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation. Nsp10 is a critical regulator of coronavirus RNA synthesis and may play an important role in polyprotein processing.
Recommended Storage: Store at less than -20°C for up to 6 months. Avoid freeze-thaw cycles.
Protein Tag: 6His, N-terminus
Protein Type: Recombinant
Purification: Greater than 80 % as determined by reducing SDS-PAGE.
Predicted Molecular Weight: 17.9 kDa
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