Description: Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of different cell types (including activated T cells, B cells, macrophages, mast cells, endothelial cells and fibroblasts) in response to cytokine or immune and inflammatory stimuli. Besides granulocyte-macrophage progenitors, GM-CSF is also a growth factor for erythroid, megakaryocyte and eosinophil progenitors. On mature hematopoietic cells, GM-CSF is a survival factor for and activates the effectors functions of granulocytes, monocytes/macrophages and eosinophils.
Presentation: Lyophilized from PBS
Protein Type: Recombinant
Reconstitution Instructions: Reconstitute in ddH2O or PBS at 100 µg/ml.
Purification: Greater than 95% by SDS-PAGE and HPLC
Predicted Molecular Weight: 15~19 kDa (SDS-PAGE)
Synonyms: CSF2, Colony-stimulating factor, CSF, GM-CSF, Molgramostin, GMCSF
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