USH1C Blocking peptide (C terminal region)

Description of Target: Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal development and maintenance of cochlear hair cell bundles (By similarity). As part of the intermicrovillar adhesion complex/IMAC plays a role in brush border differentiation, controlling microvilli organization and length. Probably plays a central regulatory role in the assembly of the complex, recruiting CDHR2, CDHR5 and MYO7B to the microvilli tips.

Product Format: Lyophilized powder

Protein Size: 403

• SKU: AVIAAP96739-100
• Manufacturer: Aviva Systems Biology
• Manufacturer SKU: AAP96739-100UG
• Green Labware: No
• Package Unit: 100µg
• Quantity Unit: STK
• Application: Western Blotting
• Human Gene ID: 10083