VRK1 Blocking peptide (C terminal region)

Description of Target: Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity.

Product Format: Lyophilized powder

Protein Size: 396

• SKU: AVIAAP96723-100
• Manufacturer: Aviva Systems Biology
• Manufacturer SKU: AAP96723-100UG
• Green Labware: No
• Package Unit: 100µg
• Quantity Unit: STK
• Application: Western Blotting
• Human Gene ID: 7443