Clone Name: MSVA-610M
Light Chain: Kappa
Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.
Go to Normal Tissue GalleryGo to Cancer Tissue Gallery
Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 59
Positive Control: Skin: All squamous epithelial cells (except the basal cell layer) should show strong cytoplasmic staining, while the basal cell layer remains KRT10 negative or shows only minimal staining.
Negative Control: Colon: All epithelial, inflammatory, stromal and muscle cells must not show any KRT10 staining.
Form: Liquid
Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for BSA and azide free format), 0.05% sodium azide.
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)
Background: This gene encodes a member of the type I (acidic) cytokeratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. Mutations in this gene are associated with epidermolytic hyperkeratosis. This gene is located within a cluster of keratin family members on chromosome 17q21. [provided by RefSeq, Jul 2008]
Uniprot ID: P13645
Antigen Species: Human
Immunogen: Recombinant full-lenth human KRT10 protein.
Purification: Protein A/G purified
Conjugation: Unconjugated
Full Name: keratin 10
English
Deutsch
