Clone Name: AEF-5
Application Note: WB: 1:5000-1:10000. ICC/IF: 1:50-1:200. IHC-P: 1:50-1:200. FACS: 1:50. IP: 1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 134
Form: Liquid
Buffer (with preservative): PBS, 150 mM NaCl, 50% glycerol, 0.4-0.5 mg/mL BSA, 0.02% sodium azide.
Concentration: Batch dependent (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq, Jun 2016]
Uniprot ID: P00533
Antigen Species: Human
Immunogen: A synthesized peptide derived from human EGFR (ErbB 1)
Purification: Purified by affinity chromatography
Conjugation: Unconjugated
Full Name: epidermal growth factor receptor
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