MALT-1(MT1/410), 1mg/mL

MALT-1(MT1/410), 1mg/mL
SKU
BTMBNUM0410-50
Packaging Unit
50 uL
Manufacturer
Biotium

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Description: Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT1) is found in extranodal low-grade B cell lymphomas. MALT1 encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT1 gene, which maps to human chromosome 18q21, and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT1 caspase-like domain. MALT1 mRNA is found in pre-B cells, mature B cells and plasma cells.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Mus musculus (mouse)

Clone: MT1/410

Entrez Gene ID: 10892

Immunogen: Human MALT1 recombinant fragment (aa701-808)

Verified AB Applications: IHC (FFPE) (verified)/WB (verified)

Z-Antibody Applications: IHC, FFPE (verified)/WB (verified)
More Information
SKU BTMBNUM0410-50
Manufacturer Biotium
Manufacturer SKU BNUM0410-50
Green Labware No
Package Unit 50 uL
Quantity Unit STK
Reactivity Human
Clonality Monoclonal
Application Western Blotting, Immunohistochemistry
Isotype IgG1 kappa
Host Mouse
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