Application Note: WB: 0.1-0.25 μg/mL. ICC/IF: 5 μg/mL. IHC-P: 2-5 μg/mL. FACS: 1-3 μg/10⁶ cells. ELISA: 0.1-0.5 μg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 53
Form: Liquid
Buffer (with preservative): 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, no preservatives.
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I). Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes. The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product. Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria. Mutations in this gene are associated with mitochondrial complex I deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009]
Uniprot ID: O75306
Antigen Species: Human
Immunogen: E.coli-derived human NDUFS2 recombinant protein (Position: M1-R463).
Conjugation: Unconjugated
Full Name: NADH:ubiquinone oxidoreductase core subunit S2
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