Conjugation: FITC: Fluorescein Isothiocyanate
Description of Target: Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature.
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CA1
Key Reference: Gambhir,K.K., Biochem. Genet. 45 (5-6), 431-439 (2007)
Molecular Weight: 29kDa
Peptide Sequence: Synthetic peptide located within the following region:
ASPDWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: Carbonic anhydrase 1
Protein Size: 261
Purification: Affinity Purified
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