Conjugation: HRP: Horseradish Peroxidase
Description of Target: CPE is a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteinsThis gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CPE
Key Reference: Wang,J., (2008) Acta Pharmacol. Sin. 29 (6), 736-744
Molecular Weight: 52kDa
Peptide Sequence: Synthetic peptide located within the following region:
GMRRRRRLQQEDGISFEYHRYPELREALVSVWLQCTAISRIYTVGRSFEGProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: Carboxypeptidase E
Protein Size: 476
Purification: Affinity Purified
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