Conjugation: FITC: Fluorescein Isothiocyanate
Description of Target: Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains.Members of the F-box protein family, such as FBXO27, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXO27
Key Reference: Jin,J., (2004) Genes Dev. 18 (21), 2573-2580
Molecular Weight: 31kDa
Peptide Sequence: Synthetic peptide located within the following region:
LDKFSAVPDPIPQWNNNACLHVTHVFSNIKMGVRFVSFEHRGQDTQFWAGProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: F-box only protein 27
Protein Size: 283
Purification: Affinity Purified
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