PE-conjugated Anti-BCL2L1 antibody(DM189); Rabbit mAb

Background: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane; and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential; and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria; both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.

Description: PE-conjugated Anti-BCL2L1 antibody(DM189); Rabbit mAb

Storage & Shipping: Store at 2°C-8°C for 6 months

Formulation & Reconstitution: Liquid，PBS with 0.05% Proclin300, 155% BSA

Target: BCL2L1

Uniprot ID: Q07817

Usage: Research use only

Clone ID: DM189

Purification: Purified from cell culture supernatant by affinity chromatography

Recommended Dilutions: Flow Cyt 1:100

• SKU: DMADME100189P-100
• Manufacturer: DIMA Biotechnology
• Manufacturer SKU: DME100189P-100
• Package Unit: 100 test
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Rabbit IgG
• Host: Rabbit
• Conjugate: Conjugated, PE (Phycoerythrin)