PE-conjugated Anti-Dxd antibody(1A1); Rabbit mAb

Background: Dxd is a potent anti-cancer drug, acting as an alkaloid camptothecin analog and a DNA topoisomerase I inhibitor. It forms a stable complex with topoisomerase I and DNA, impeding DNA replication and inducing cancer cell death. Dxd is utilized as a payload in specific antibody-drug conjugates (ADCs), with examples such as trastuzumab deruxtecan targeting HER2 and patritumab deruxtecan targeting HER3.

Description: PE-conjugated Anti-Dxd antibody(1A1); Rabbit mAb

Storage & Shipping: Store at 2°C-8°C for 6 months

Formulation & Reconstitution: Liquid，PBS with 0.05% Proclin300, 357% BSA

Target: Dxd

Uniprot ID: N.A.

Usage: Research use only

Clone ID: 1A1

Purification: Purified from cell culture supernatant by affinity chromatography

Recommended Dilutions: Flow Cyt 1:100

• SKU: DMADME101024P-100
• Manufacturer: DIMA Biotechnology
• Manufacturer SKU: DME101024P-100
• Package Unit: 100 test
• Quantity Unit: STK
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Rabbit IgG
• Host: Rabbit
• Conjugate: Conjugated, PE (Phycoerythrin)