Background: The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease. [provided by RefSeq, Jul 2008]
Description: PE-conjugated Anti-IL1A antibody(4G2); IgG1 Chimeric mAb
Storage & Shipping: Store at 2°C-8°C for 6 months
Formulation & Reconstitution: Liquid,PBS with 0.05% Proclin300, 311% BSA
Target: IL1A
Uniprot ID: P01583
Usage: Research use only
Clone ID: 4G2
Purification: Purified from cell culture supernatant by affinity chromatography
Recommended Dilutions: Flow Cyt 1:100