PE-conjugated Anti-PCSK9 antibody(DMC222); IgG1 Chimeric mAb

Background: This gene encodes a member of the subtilisin-like proprotein convertase family; which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver; intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants.

Description: PE-conjugated Anti-PCSK9 antibody(DMC222); IgG1 Chimeric mAb

Storage & Shipping: Store at 2°C-8°C for 6 months

Formulation & Reconstitution: Liquid，PBS with 0.05% Proclin300, 185% BSA

Target: PCSK9

Uniprot ID: Q8NBP7

Usage: Research use only

Clone ID: DMC222

Purification: Purified from cell culture supernatant by affinity chromatography

Recommended Dilutions: Flow Cyt 1:100

• SKU: DMADMC100222P-100
• Manufacturer: DIMA Biotechnology
• Manufacturer SKU: DMC100222P-100
• Package Unit: 100 test
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Flow Cytometry
• Isotype: Rabbit/Human Fc chimeric IgG1
• Host: Rabbit
• Conjugate: Conjugated, PE (Phycoerythrin)