Conjugation: FITC: Fluorescein Isothiocyanate
Description of Target: Receptor-regulated class I phosphoinositide 3-kinases (PI3Ks) phosphorylate the membrane lipid phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to PtdIns(3,4,5)P3, which in turn recruits and activates cytosolic effectors involved in proliferation, survival, or chemotaxis. PIK3R5 is a PI3K regulatory subunit.Receptor-regulated class I phosphoinositide 3-kinases (PI3Ks) phosphorylate the membrane lipid phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) to PtdIns(3,4,5)P3, which in turn recruits and activates cytosolic effectors involved in proliferation, survival, or chemotaxis. PIK3R5 is a PI3K regulatory subunit (Brock et al., 2003 [PubMed 12507995]).[supplied by OMIM]. Sequence Note: removed 2 bases from the 3' end that did not align to the reference genome assembly. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-3253 AF128881.1 1-3253
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PIK3R5
Key Reference: Johnson,C., (2007) Oncogene 26 (49), 7049-7057
Molecular Weight: 97kDa
Peptide Sequence: Synthetic peptide located within the following region:
HRFLTWPVPYCSICQELLTFIDAELKAPGISYQRLVRAEQGLPIRSHRSSProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: Phosphoinositide 3-kinase regulatory subunit 5
Protein Size: 880
Purification: Affinity Purified
Subunit: 5
English
Deutsch
