Conjugation: HRP: Horseradish Peroxidase
Description of Target: POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging. POLE3 is a histone-fold protein that interacts with other histone-fold proteins to bind DNA in a sequence-independent manner. These histone-fold protein dimers combine within larger enzymatic complexes for DNA transcription, replication, and packaging.[supplied by OMIM].
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human POLE3
Key Reference: Olsen,J.V., (2006) Cell 127 (3), 635-648
Molecular Weight: 17kDa
Peptide Sequence: Synthetic peptide located within the following region:
AERPEDLNLPNAVITRIIKEALPDGVNISKEARSAISRAASVFVLYATSCProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: DNA polymerase epsilon subunit 3
Protein Size: 147
Purification: Affinity Purified
Subunit: 3