STING antibody (MSVA-515M) HistoMAX™

Clone Name: MSVA-515M

Light Chain: Kappa

Product Description: This antibody was validated on 76 different Normal and cancerTissues by IHC-P.

Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 42

Positive Control: Adrenal gland: Endothelial cells and macrophages should show a moderate to strong STING positivity.

Negative Control: Adrenal gland: Adrenocortical and medullary cells should not show STING staining (Note: in case of tissue damage aberrant STING staining may occur).

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for sodium azide-free or sodium azide and BSA-free format), 0.05% sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]

Uniprot ID: Q86WV6

Antigen Species: Human

Immunogen: Recombinant fragment (around aa190-290) of human TMEM173 protein

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: transmembrane protein 173

• SKU: GTX04484-S-100
• Manufacturer: GeneTex
• Manufacturer SKU: GTX04484-S-100
• Green Labware: No
• Package Unit: 100 μl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Immunohistochemistry (paraffin)
• Isotype: IgG2c
• Human Gene ID: 340061
• Host: Mouse