Conjugation: HRP: Horseradish Peroxidase
Description of Target: TBX6 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx6. Knockout experiments in mice indicate that Tbx6 is important for specification of paraxial mesoderm structures. This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene is the human ortholog of mouse Tbx6. Knockout experiments in mice indicate that Tbx6 is important for specification of paraxial mesoderm structures. Transcript variants encoding different isoforms have been noted for this gene.
Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TBX6
Key Reference: Ghebranious,N., (er) J. Bone Miner. Res. (2008) In press
Molecular Weight: 47kDa
Peptide Sequence: Synthetic peptide located within the following region:
PSHLPTRSPSFPEAPDSGRSAPYSAAFLELPHGSGGSGYPAAPPAVPFAPProduct Format: Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Protein Name: T-box transcription factor TBX6
Protein Size: 436
Purification: Affinity Purified
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