TCF7L1 Antibody - N-terminal region : FITC

Conjugation: FITC: Fluorescein Isothiocyanate

Description of Target: TCF7L1 participates in the Wnt signaling pathway. It binds to DNA and acts as a repressor in the absence of CTNNB1, and as an activator in its presence. It is necessary for the terminal differentiation of epidermal cells, the formation of keratohyalin granules and the development of the barrier function of the epidermis. TCF7L1 down-regulates NQO1, leading to increased mitomycin c resistance.

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TCF7L1

Key Reference: Hillier,L.W., (2005) Nature 434 (7034), 724-731

Molecular Weight: 63kDa

Peptide Sequence: Synthetic peptide located within the following region: ESENQSSSSDSEAERRPQPVRDTFQKPRDYFAEVRRPQDSAFFKGPPYPG

Product Format: Liquid. Purified antibody supplied in 1x PBS buffer.

Protein Name: Transcription factor 7-like 1

Protein Size: 588

Purification: Affinity Purified

• SKU: AVIARP57917_P050FITC
• Manufacturer: Aviva Systems Biology
• Manufacturer SKU: ARP57917_P050-FITC
• Green Labware: No
• Package Unit: 100μl
• Quantity Unit: STK
• Reactivity: Human, Mouse (Murine), Rat (Rattus), Rabbit, Dog (Canine), Cow (Bovine)
• Clonality: Polyclonal
• Application: Western Blotting
• Human Gene ID: 83439
• Host: Rabbit