Conjugation: FITC: Fluorescein Isothiocyanate
Description of Target: VTN is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human VTN
Key Reference: Upton,Z., (2008) J. Invest. Dermatol. 128 (6), 1535-1544
Molecular Weight: 52kDa
Peptide Sequence: Synthetic peptide located within the following region:
EDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEEEProduct Format: Liquid. Purified antibody supplied in 1x PBS buffer.
Protein Name: Vitronectin
Protein Size: 478
Purification: Affinity Purified