PVRL4 antibody (HL2758)

Clone Name: HL2758

Light Chain: Kappa

Application Note: WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 55

Specificity/Sensitivity: This antibody was raised against human PVRL4 Extracellular domain.

Form: Liquid

Buffer (with preservative): PBS, no Preservative.

Concentration: batch dependent (Please refer to the vial label for the specific concentration.)

Background: This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011]

Uniprot ID: Q96NY8

Antigen Species: Human

Immunogen: Recombinant protein encompassing a sequence within the Extracellular domain of human PVRL4. The exact sequence is proprietary.

Purification: Affinity purified by Protein A.

Conjugation: Unconjugated

Full Name: nectin cell adhesion molecule 4

• SKU: GTX639621-S-25
• Manufacturer: GeneTex
• Manufacturer SKU: GTX639621-S-25
• Green Labware: No
• Package Unit: 25 μl
• Quantity Unit: STK
• Reactivity: Human
• Clonality: Monoclonal
• Application: Western Blotting
• Isotype: IgG
• Human Gene ID: 81607
• Host: Rabbit