Clone Number: SQab1723
Immunogen: Synthetic peptide around the C-terminus of CD30.
Concentration: n/a
Format: Affinity purification with immunogen.
Storage buffer: PBS, 0.01% Sodium azide, 40% Glycerol and 0.05% BSA.
Additional info: Application note: IHC-P: Antigen Retrieval: Heat mediation was performed using Tris/EDTA buffer (pH 9.0)* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.Storage instruction: For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.Background: CD30 is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Applications: IHC-P
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