Abbreviation: CD11c
Target Synonym: Integrin alpha-X;Itgax;CD11 antigen-like family member C;Leukocyte adhesion receptor p150+95;CD11c;
Conjugation: Elab Fluor® Red 780
Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 ug/10^6 cells in 100 uL volume].
Clone NO.: N418
UNIProt ID: Q9QXH4
Background: CD11c is a 150 kD glycoprotein also known as αX integrin, CR4, and p150. CD11c forms a αXβ2 heterodimer with β2 integrin (CD18). It is primarily expressed on dendritic cells, NK cells, a subset of intestinal intraepithelial lymphocytes (IEL), and some activated T cells. The αXβ2 integrin plays an important role in cell-cell contact by binding its ligands: iC3b, fibrinogen and CD54.
Concentration: 0.5 mg/mL
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